The end of history will be a very sad time. The struggle for recognition, the willingness to risk one's life for a purely abstract goal, the worldwide ideological struggle that called forth daring, courage, imagination, and idealism, will be replaced by economic calculation, the endless solving of technical problems, environmental concerns, and the satisfaction of sophisticated consumer demands.

出自先秦《荀子·礼论》。生是人的开始，死是人的终结。开始与终结都做得好，那么他的为人之道就完善了。说明意在劝人行仁行善，要善始善终。

在科学中，进步往往是通过质疑既定教条并敢于提出新想法来实现的。