People must feel that the natural world is important and valuable and beautiful and wonderful and an amazement and a pleasure.
The measurement problem in quantum mechanics is not a flaw in the theory, but a profound insight into the nature of reality.
"The universe is asymmetric and I am persuaded that life, as it is known to us, is a direct result of the asymmetry of the universe or of its indirect consequences."
The best way to be successful is to be persistent.