我四十而立之时，总觉得，当回顾我的一生，我会看到一系列的决定，一些是我仔细思考后作出的，一些是我无意而为的，还有很多是我根本无法掌控的。

当你能永远活着时，你为了什么而活？

——《致鲁赛尔函》（1906年11月8日）

The end of history will be a very sad time. The struggle for recognition, the willingness to risk one's life for a purely abstract goal, the worldwide ideological struggle that called forth daring, courage, imagination, and idealism, will be replaced by economic calculation, the endless solving of technical problems, environmental concerns, and the satisfaction of sophisticated consumer demands.

Humans are allergic to change. They love to say, 'We've always done it this way.' I try to fight that. That's why I have a clock on my wall that runs counter-clockwise.

I don't chase trends, I create them.

创新不仅仅是创造新药，更是改变生活。