与孟子不同，荀子主张“性恶”，认为人性本恶。因而更强调人为的作用，通过后天的人为的努力才能达到“善”。没有本性那么人为的努力就不能对症下药，没有人为的努力，本性就不能改善。所以主张“性伪合”，天生的本性和后天的努力对人都有重要影响，而后天的努力更为重要，它是我们能够自己掌控的，“学不可以已”的意义就更大。
The first erroneous assumption is that quality means goodness, or luxury, or shininess, or weight. Quality means conformance to requirements.
Quality is more important than quantity. One home run is much better than two doubles.
The future of CRISPR is bright, and I believe it will continue to revolutionize medicine and agriculture.