Sustainability in pharma isn’t an option—it’s an obligation.

The most sustainable building is the one that is already built.

The only way to deal with an unfree world is to become so absolutely free that your very existence is an act of rebellion.

Trend-following is not such a good model. It’s simply eroded. Things change and being able to adjust is what made Mr. Simons so successful. “Statistic predictor signals erode over the next several years； it can be five years or 10 years. You have to keep coming up with new things because the market is against us. If you don’t keep getting better， you’re going to do worse.